2-Sulfanylidene-1,2-dihydropyridine-3-carbohydrazide
نویسندگان
چکیده
All non-H atoms of the title compound, C(6)H(7)N(3)OS, which exists in the thione form, lie in a common plane (r.m.s. of non-H atoms = 0.08 Å). The amino group of the -NH-NH(2) substituent forms an intra-molecular hydrogen bond to the S atom. The terminal -NH(2) group is pyramidally coordinated; it forms a weak N-H⋯O and a weak N-H⋯S hydrogen bond. Furthermore, the N atom is an acceptor for a C-H⋯N contact. The amino group of the ring is a hydrogen-bond donor to the carbonyl O atom of an adjacent mol-ecule, this inter-action giving rise to a linear chain motif running along the b axis.
منابع مشابه
Synthesis and antibacterial activity of novel 5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine-2-carbohydrazide derivatives
BACKGROUND The intensely increasing multi-drug resistant microbial infections have encouraged the search for new antimicrobial agents. Hydrazone derivatives are known to exhibit a wide variety of biological activities including anti-microbial. In heterocyclic moiety, imidazo[1,2-a]pyrimidines are the subject of immense interest for their antimicrobial activity and also for their analgesic, anti...
متن کامل1-(3-Ethylphenyl)-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
In the title compound, C(16)H(16)N(2)O, the essentially planar 1,2-dihydro-pyridine ring [maximum deviation = 0.021 (1) Å] makes a dihedral angle of 85.33 (8)° with the benzene ring. In the crystal, mol-ecules are linked into a chain along the b axis via C-H⋯O inter-actions.
متن کاملTetraaquabis(2-oxo-1,2-dihydropyridine-5-sulfonato-κO 2)zinc(II)
The metal atom in the title compound, [Zn(C(5)H(4)NO(4)S)(2)(H(2)O)(4)], lies on a center of inversion and is linked to the anionic ligand through the carbonyl O atom. In the crystal structure, the 2-oxo-1,2-dihydro-pyridine-5-sulfon-ate ligand inter-acts with other mol-ecules through N-H⋯O and O-H⋯O hydrogen bonds, forming a three-dimensional network structure.
متن کاملDistribution of [1,2-3H]cholesterol in mouse brain after injection in the suckling period
Glutaraldehyde-carbohydrazide polymer (GACH) was used to embed olfactory tracts, trapezoid body, and sciatic nerves of 9-, 10-, and 49-day old mice 2 h, 24 h, and 6 wk (respectively) after the intraperitoneal administration of [1,2-3H]cholesterol. Greater than 94% of radioactive cholesterol was retained in the GACH-infiltrated brain 24 h or more after injection. The fine structural preservation...
متن کاملN′-[(E)-1-(4-Bromophenyl)ethylidene]-4-hydroxy-2-methyl-1,1-dioxo-2H-1,2-benzothiazine-3-carbohydrazide
The six-membered heterocycle in the title compound, C(18)H(16)BrN(3)O(4)S, adopts a sofa conformation. Intra-molecular N-H⋯N and O-H⋯O hydrogen bonds stabilize the mol-ecular conformation by forming a five- and a six-membered ring, respectively. The crystal packing is stabilized by inter-molecular C-H⋯O hydrogen bonds.
متن کامل